个人概况:
宋尔群,博士,教授,博士研究生导师。入选教育部国家级青年人才(2019年),重庆市杰出青年基金获得者(2021年),重庆市创新青年科技人才培养计划(2014年)。获2021年中国青年报社、中国科学技术传播中心“强国青年科学家”提名奖,2010年全国优秀博士论文提名奖,2013年西南大学青年教师成才奖。“重大疾病诊疗精准成像分析”重庆市高校创新研究群体负责人(2021年)。
教育和工作经历:
1999年-2003年:湖南师范大学,理学学士
2003年-2008年:武汉大学,分析化学,理学博士
2011年-2012年:美国University of Florida(佛罗里达大学)化学系、生物/纳米交叉研究中心访问学者
2008年-至今: 西南大学药学院
主要社会兼职:
中国化学会高级会员。《中国化学快报》、《分析测试学报》、《Journal of Analysis and Testing》青年编委。国家自然科学基金、教育部CJ学者奖励计划、青年拔尖人才和学位中心学位论文等通讯评议人。担任Advanced Functional Materials, Analytical Chemistry, Trends in Analytical Chemistry等多个期刊审稿人。
课题组研究方向:
(1)光-磁功能探针设计与传感(侧重疾病相关标志物分析)
(2)活细胞/活体致病菌感染原位成像及抑菌策略
课题组主持研究的主要科研项目:
1. 国家自然科学基金面上项目(22174116,2022.01-2025.12)
2. 国家自然科学基金面上项目(21974110,2020.01-2023.12)
3. 国家自然科学基金面上项目(21575118,2016.1-2019.12)
4. 国家自然科学基金青年基金(21005064,2011.1-2013.12)
5. 重庆市杰出青年基金项目(cstc2021jcyj-jqx0024,2021.9-2024.8)
6. 重庆市自然科学基金项目(cstc2019jcyj-msxmX0406,2019.7-2021.4)
7. 重庆市创新青年科技人才培养项目(cstc2014kjrc-qnrc00001,2015.1-2017.12)
8. 重庆市自然科学基金项目(cstc2010BB1135,2010.10-2013.10)
9. 化学生物传感与计量学国家重点实验室开放基金(2012009,2013.3-2015.3)
10. 西南大学“科技新星”专项资助项目(2016.07-2019.12)
11. 中央高校基本科研业务费优青培育项目(XDJK2017A017,2017.3-2019.12)
12. 中央高校基本科研业务费重大项目(XDJK2015A017,2015.5-2017.12)
近期主要代表论文:
1. Li, L.; Liu, M.; Deng, S.; Zhu, X.; Song, Y.; Song, E., Enzyme-Triggered Transforming of Assembly Peptide-Modified Magnetic Resonance-Tuned Probe for Highly Sensitive Imaging of Bacterial Infection In Vivo. Small 2023, 2208249.
2. Zhang, Y.; Hao, M.; Li, L.; Luo, Q.; Deng, S.; Yang, Y.; Liu, Y.; Fang, W.; Song, E., Research progress of contrast agents for bacterial infection imaging in vivo. TrAC Trends in Analytical Chemistry 2023, 159, 116916.
3. Liao, Z. Y.; Han, L.; Li, Q. J.; Li, L. Y.; Liu, Y.; Song, Y.; Tan, W.H.; Song, E. Q.* Gradient magnetic separation and fluorescent imaging-based heterogeneous circulating tumor cell subpopulations assay with biomimetic multifunctional nanoprobes. Advanced Functional Materials 2021, 2009937.
4. Li, L.; Gu, P.; Hao, M.; Xiang, X.; Feng, Y.; Zhu, X.; Song, Y.; Song, E. Q.* Bacteria-targeted MRI probe-based imaging bacterial infection and monitoring antimicrobial therapy in vivo. Small 2021, 2103627
5. Hu, Y. Y.; Guo, X.; Gu, P. L.; Luo, Q.; Song, Y.; Song, E. Q.* Mn2+-mediated magnetic relaxation switching for direct assay of ctDNA in whole blood via exonuclease III assisted amplification. Sensors and Actuators: B. Chemical 2021, 330,129340.
6. Tao, X. Q.; Liao, Z. Y.; Zhang, Y. Q.; Fu, F.; Hao, M.Q.; Song, Y.; Song, E. Q.*. Aptamer-quantum dots and teicoplanin-gold nanoparticles constructed FRET sensor for sensitive detection of Staphylococcus aureus. Chinese Chemical Letters 2021, 32, 2,791-795.
7. Li, Q. J.; Liao, Z. Y.; Han, L.; Li, L. Y.; Song, Y.; Song, E. Q.* Isolation and analysis of tumor cell subpopulations using biomimetic immuno-fluorescent magnetic multifunctional nanoprobes. Advanced Functional Materials 2020, 202004963.
8. Tao, X.Q.; Chang, X.X.; Wan, X.L.; Guo, Y.N.; Zhang, Y.Q.; Liao, Z.Y.; Song, Y.*; Song, E. Q.* Impact of Protein Corona on Noncovalent Molecule-Gold Nanoparticle-Based Sensing. Analytical Chemistry 2020, 92, 22, 14990-14998.
9. Fu, F.; Zhang, Y. Q.; Li, L. Y.; Wang, H.; Li, Q. J.; Tao, X. Q.; Song, Y.; Song, E. Q.* Intracellular pathogen detection based on dual-Recognition units Constructed Fluorescence Resonance Energy Transfer Nanoprobe. Analytical Chemistry 2020, 92(16),11462-11468.
10. Hu, Y. Y.; Guo, X.; Wang, H.; Luo, Q.; Song, Y.; Song, E. Q.* Magnetic-separation assisted magnetic relaxation switching assay for mercury ion based on the concentration change of oligonucleotide functionalized magnetic nanoparticle. ACS Applied Bio Materials 2020, 3, 2651-2657.
11. Li, L.; Li, Q.; Liao, Z.; Sun, Y.; Cheng, Q.; Song, Y.; Song, E.Q.*, Tan. W. Magnetism-Resolved Separation and Fluorescence Quantification for Near-Simultaneous Detection of Multiple Pathogens. Analytical Chemistry 2018, 90, 9621-9628.
12. Fu, F.; Li, L.; Luo, Q.; Li, Q.; Yu, M.; Song, Y.; Song, E.Q.* Selective and sensitive detection of lysozyme based on plasmon resonance light-scattering of hydrolyzed peptidoglycan stabilized-gold nanoparticles. Analyst 2018, 143, 1133-1140.
13. Yu, M.; Wang, H.; Fu, F.; Li, L.; Li, J.; Li, G.; Song, Y.; Swihart, M. T.; Song, E.Q.* A Dual Recognition FRET-based Platform for One-Step Sensitive Detection of Pathogenic Bacteria using Fluorescent Vancomycin-Gold Nanoclusters and Aptamer-Gold Nanoparticles. Analytical Chemistry 2017, 89 (7), 4085-4090.
14. Yu, M.; Zhu, Z.; Wang, H.; Li, L.; Fu, F.; Song, Y.; Song, E. Q.* Mediated facile one-pot synthesis of gold nanoclusters as fluorescent sensor for ferric ion. Biosensors and Bioelectronics 2017, 91, 143-148.
15. Cheng, D.; Yu, M. Q.; Fu, F.; Han, W.; Li, G.; Xie, J.; Song, Y.; Swihart, M. T.; Song, E. Q.*A dual recognition strategy for specific and sensitive detection of bacteria using aptamer coated magnetic beads and antibiotic-capped gold nanoclusters. Analytical Chemistry 2016, 88, 820-825.
16. Song, E. Q.;* Yu, M. Q.; Wang, Y.Y.; Hu, W. H.; Cheng, D.; Swihart, M. T.; Song, Y. Multicolor quantum dot based fluorescence immunoassay array for simultaneous visual detection of multiple antibiotic residues in milk. Biosensors and Bioelectronics 2015, 72, 320-325.
17. Song, E. Q.;* Han, W.; Li, J.; Jiang, Y.; Cheng, D.; Song, Y.; Zhang, P.; Tan, W. H. Magnetic encoded fluorescent multifunctional nanospheres for simultaneous multicomponent analysis. Analytical Chemistry 2014, 86, 9434-9442.
授权专利:
1. 宋尔群,宋杨. 磁编码的荧光-磁性多功能纳米复合物及其制备方法,专利号:ZL 2013 1 0344477.7, 授权日期:2014.12.24
2. 宋尔群,余梦群,宋杨,替考拉宁功能化纳米金的制备方法及其产品和应用,专利号:ZL 2016 1 0488526.8,授权日期:2019.8.6
招生招聘:
热忱欢迎有志于感染性疾病诊疗相关基础研究与应用开发的青年教师、博士后、研究生和本科生加入课题组!
联系方式:
电子信箱:eqsong@swu.edu.cn, 77949883@qq.com
通信地址:重庆市北碚区西南大学药学院, 400715