Personal profile:
Erqun Song, PhD, is a professor and supervisor of PhD students. She was selected as a national young talent of the Ministry of Education (2019), a recipient of Chongqing Outstanding Youth Fund (2021), and Chongqing Innovative Young Scientist Training Program (2014). She was nominated by China Youth Daily and China Center for Science and Technology Communication for the "Strong Young Scientist" award in 2021, nominated for the National Outstanding Doctoral Dissertation Award in 2010, and the Young Teacher Achievement Award of Southwest University in 2013. Leader of Chongqing University Innovation Research Group on "Precision Imaging Analysis for Major Disease Diagnosis" (2021).
Education and work experience:
1999-2003: Hunan Normal University, Bachelor of Science
2003-2008: Wuhan University, Analytical Chemistry, Doctor of Science
2011-2012: Visiting Scholar, Department of Chemistry, Center for Bio/Nano Intersectional Research, University of Florida (USA)
2008-Present: School of Pharmacy, Southwest University
Main social concurrent positions:
Senior Member of the Chinese Chemical Society. Young editorial board member of Chinese Chemical Express, Journal of Analysis and Testing, and Journal of Analysis and Testing. She is a corresponding reviewer for the National Natural Science Foundation of China, the CJ Scholars Award Program of the Ministry of Education, Young Talent and Dissertation of the Degree Center. She is a reviewer for Advanced Functional Materials, Analytical Chemistry, Trends in Analytical Chemistry and many other journals.
Research interests of the group include
(1) Optical-magnetic functional probe design and sensing (with a focus on disease-related marker analysis)
(2) In situ imaging of live cells/in vivo pathogenic bacteria infection and inhibition strategies
The main scientific projects that the group has conducted research on:
1. National Natural Science Foundation of China (22174116, 2022.01-2025.12)
2. National Natural Science Foundation of China (21974110, 2020.01-2023.12)
3. National Natural Science Foundation of China (21575118, 2016.1-2019.12)
4. National Natural Science Foundation of China Youth Fund (21005064, 2011.1-2013.12)
5. Outstanding Youth Foundation of Chongqing (cstc2021jcyj-jqx0024, 2021.9-2024.8)
6. Chongqing Natural Science Foundation Project (cstc2019jcyj-msxmX0406, 2019.7-2021.4)
7. Chongqing Innovative Youth Science and Technology Talent Training Project (cstc2014kjrc-qnrc00001, 2015.1-2017.12)
8. Project of Chongqing Natural Science Foundation (cstc2010BB1135, 2010.10-2013.10)
9. Open Fund of State Key Laboratory of Chemical Biosensing and Metrology (2012009, 2013.3-2015.3)
10. "New Star of Science and Technology" Project of Southwest University (2016.07-2019.12)
11. Project of the Central Universities Basic Scientific Research Business Fund for the Cultivation of Excellent Youth (XDJK2017A017, 2017.3-2019.12)
12. Major Project of Basic Scientific Research Funds of the Central Universities (XDJK2015A017, 2015.5-2017.12)
Recent major representative papers:
1. Li, L.; Liu, M.; Deng, S.; Zhu, X.; Song, Y.; Song, E., Enzyme-Triggered Transforming of Assembly Peptide-Modified Magnetic Resonance-Tuned Probe for Highly Sensitive Imaging of Bacterial Infection In Vivo. Small 2023, 2208249.
2. Zhang, Y.; Hao, M.; Li, L.; Luo, Q.; Deng, S.; Yang, Y.; Liu, Y.; Fang, W.; Song, E., Research progress of contrast agents for bacterial infection imaging in vivo. TrAC Trends in Analytical Chemistry 2023, 159, 116916.3. Liao, Z. Y.; Han, L.; Li, Q. J.; Li, L. Y.; Liu, Y.; Song, Y.; Tan, W.H.; Song, E. Q.* Gradient magnetic separation and fluorescent imaging-based heterogeneous circulating tumor cell subpopulations assay with biomimetic multifunctional nanoprobes. Advanced Functional Materials 2021, 2009937.
4. Li, L.; Gu, P.; Hao, M.; Xiang, X.; Feng, Y.; Zhu, X.; Song, Y.; Song, E. Q.* Bacteria-targeted MRI probe-based imaging bacterial infection and monitoring antimicrobial therapy in vivo. Small 2021, 2103627
5. Hu, Y. Y.; Guo, X.; Gu, P. L.; Luo, Q.; Song, Y.; Song, E. Q.* Mn2+-mediated magnetic relaxation switching for direct assay of ctDNA in whole blood via exonuclease III assisted amplification. Sensors and Actuators: B. Chemical 2021, 330,129340.
6. Tao, X. Q.; Liao, Z. Y.; Zhang, Y. Q.; Fu, F.; Hao, M.Q.; Song, Y.; Song, E. Q.*. Aptamer-quantum dots and teicoplanin-gold nanoparticles constructed FRET sensor for sensitive detection of Staphylococcus aureus. Chinese Chemical Letters 2021, 32, 2,791-795.
7. Li, Q. J.; Liao, Z. Y.; Han, L.; Li, L. Y.; Song, Y.; Song, E. Q.* Isolation and analysis of tumor cell subpopulations using biomimetic immuno-fluorescent magnetic multifunctional nanoprobes. Advanced Functional Materials 2020, 202004963.
8. Tao, X.Q.; Chang, X.X.; Wan, X.L.; Guo, Y.N.; Zhang, Y.Q.; Liao, Z.Y.; Song, Y.*; Song, E. Q.* Impact of Protein Corona on Noncovalent Molecule-Gold Nanoparticle-Based Sensing. Analytical Chemistry 2020, 92, 22, 14990-14998.
9. Fu, F.; Zhang, Y. Q.; Li, L. Y.; Wang, H.; Li, Q. J.; Tao, X. Q.; Song, Y.; Song, E. Q.* Intracellular pathogen detection based on dual-Recognition units Constructed Fluorescence Resonance Energy Transfer Nanoprobe. Analytical Chemistry 2020, 92(16),11462-11468.
10. Hu, Y. Y.; Guo, X.; Wang, H.; Luo, Q.; Song, Y.; Song, E. Q.* Magnetic-separation assisted magnetic relaxation switching assay for mercury ion based on the concentration change of oligonucleotide functionalized magnetic nanoparticle. ACS Applied Bio Materials 2020, 3, 2651-2657.
11. Li, L.; Li, Q.; Liao, Z.; Sun, Y.; Cheng, Q.; Song, Y.; Song, E.Q.*， Tan. W. Magnetism-Resolved Separation and Fluorescence Quantification for Near-Simultaneous Detection of Multiple Pathogens. Analytical Chemistry 2018, 90, 9621-9628.
12. Fu, F.; Li, L.; Luo, Q.; Li, Q.; Yu, M.; Song, Y.; Song, E.Q.* Selective and sensitive detection of lysozyme based on plasmon resonance light-scattering of hydrolyzed peptidoglycan stabilized-gold nanoparticles. Analyst 2018, 143, 1133-1140.
13. Yu, M.; Wang, H.; Fu, F.; Li, L.; Li, J.; Li, G.; Song, Y.; Swihart, M. T.; Song, E.Q.* A Dual Recognition FRET-based Platform for One-Step Sensitive Detection of Pathogenic Bacteria using Fluorescent Vancomycin-Gold Nanoclusters and Aptamer-Gold Nanoparticles. Analytical Chemistry 2017, 89 (7), 4085-4090.
14. Yu, M.; Zhu, Z.; Wang, H.; Li, L.; Fu, F.; Song, Y.; Song, E. Q.* Mediated facile one-pot synthesis of gold nanoclusters as fluorescent sensor for ferric ion. Biosensors and Bioelectronics 2017, 91, 143-148.
15. Cheng, D.; Yu, M. Q.; Fu, F.; Han, W.; Li, G.; Xie, J.; Song, Y.; Swihart, M. T.; Song, E. Q.*A dual recognition strategy for specific and sensitive detection of bacteria using aptamer coated magnetic beads and antibiotic-capped gold nanoclusters. Analytical Chemistry 2016, 88, 820-825.
16. Song, E. Q.;* Yu, M. Q.; Wang, Y.Y.; Hu, W. H.; Cheng, D.; Swihart, M. T.; Song, Y. Multicolor quantum dot based fluorescence immunoassay array for simultaneous visual detection of multiple antibiotic residues in milk. Biosensors and Bioelectronics 2015, 72, 320-325.
17. Song, E. Q.;* Han, W.; Li, J.; Jiang, Y.; Cheng, D.; Song, Y.; Zhang, P.; Tan, W. H. Magnetic encoded fluorescent multifunctional nanospheres for simultaneous multicomponent analysis. Analytical Chemistry 2014, 86, 9434-9442.
Patents granted:
1. Song Erqun, Song Yang. Magnetically encoded fluorescent-magnetic multifunctional nanocomplex and its preparation method, Patent No.: ZL 2013 1 0344477.7, Granted: 2014.12.24
2. Song Erqun, Yu Mengqun, Song Yang, Preparation method of ticoranine functionalized nano-gold and its products and applications, Patent No. ZL 2016 1 0488526.8, Grant date: 2019.8.6
Recruitment of students:
We warmly welcome young faculty, postdocs, graduate and undergraduate students who are interested in basic research and application development related to the diagnosis and treatment of infectious diseases to join the group!
Contact information:
E-mail: eqsong@swu.edu.cn, 77949883@qq.com
Address: School of Pharmacy, Southwest University, Beibe, Chongqing 400715, China
